Características metabólicas de personas con prediabetes

Rosa Pando-Álvarez; Fausto Garmendia-Lorena; Alicia Fernández-Giusti; Nelly Castro-Tutaya

doi:10.33734/diagnostico.v63i1.498

Authors

Rosa Pando-Álvarez Servicio de Endocrinología, Hospital Nacional Dos de Mayo https://orcid.org/0000-0002-6513-8743
Fausto Garmendia-Lorena Académico Honorario, Academia Nacional de Medicina. Docente Extraordinario Experto, Facultad de Medicina, Universidad Nacional Mayor de San Marcos https://orcid.org/0000-0002-6513-8743
Alicia Fernández-Giusti Vice-Decana, Facultad de Medicina, UNMSM https://orcid.org/0000-0002-6945-0582
Nelly Castro-Tutaya 4Servicio de Endocrinología, Hospital San Juan de Lurigancho https://orcid.org/0009-0001-2075-2256

DOI:

https://doi.org/10.33734/diagnostico.v63i1.498

Keywords:

Prediabetes, metabolism, risk, cardiovascular

Abstract

Objective: To study the metabolic characteristics of people with prediabetes and compare them with those of a control
group. Material and methods: A total of 105 people have been studied, 57 with prediabetes (prediab), 27 women and 30 men, and 48 people without prediab, 27 women and 21 men, whose anthropometric and blood measurements were taken. measured basal glucose (G0), at 60 and 120 minutes postprandial, basal (I0) and postprandial insulin (Ipp), total cholesterol (TC), HDL
cholesterol (HDL), triglycerides (Tg), transaminases (TGO, TGP), vitamin D (VD), parathormone (PTH) by conventional
methods; the HOMA index, the VLDL, LDL and NoHDL fractions were calculated. Results: People with prediab had
significantly higher average weight, BMI, G0, G60 and G120 than those without prediab; there were no differences in the other
biochemical markers studied. Conclusions: People with prediabetes have a higher cardiometabolic risk than those without
prediabetes.